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Organic Synthetic Materials N-Iodosuccinimide CAS 516-12-1 Organic Synthesis Sulfur Oxidation Titration Reagent Iodination Reagent
Introduction:
N-iodosuccinimide, commonly abbreviated NIS, is a white needle-shaped crystal.
NIS is an important electrophilic iodination reagent in organic chemistry. It can react with alkenyl aluminum intermediates to prepare alkenyl iodide compounds. It can also be used as an oxidizing reagent to oxidize and cyclize dipeptides to prepare β-lactams. NIS is a good iodination reagent that can smoothly convert vinyl silane and vinyl stannane into the corresponding vinyl iodide. In addition, under mild conditions, olefin boronic acid reacts with NIS to convert into olefin iodide with unchanged geometric configuration. NIS is easy to decompose and should be stored at low temperature, away from light and moisture under nitrogen protection. When using, take necessary measures to prevent inhalation of powder with pungent odor.
Uses:
1. Used in organic synthesis, sulfur oxidation titration reagent, mild iodination agent, glucosinolate catalyst, etc.
2. Mainly used as a pharmaceutical intermediate in biopharmaceuticals. N-iodosuccinimide is used as an iodination agent in chemical synthesis.
| Product Name | N-Iodosuccinimide |
| CAS | 516-12-1 |
| MF | C4H4INO2 |
| MW | 224.98 |
| EINECS | 208-221-6 |
| Color | white crystalline powder |
